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Multi-Drug Resistance Genes in the Management of Neoplastic Disease

โœ Scribed by Jane Stewart; Neil T. Gorman


Book ID
114951605
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
1006 KB
Volume
5
Category
Article
ISSN
0891-6640

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## Objective: To screen and clone multi-drug resistance (mdr) related genes in mdr acute myeloid leukemia cells (hl-60/mdr). ## Methods: Hl-60/mdr was established using all-trans retinoic acid. with the hl-60 cells as "tester" and hl60/mdr as "driver", the cdna library of hl-60/mdr was establishe