Suppression of multi-drug resistance gen
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Alison L. Russell; Colin J. Henderson; Gillian Smith; C. Roland Wolf
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Article
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1994
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John Wiley and Sons
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French
โ 569 KB
P-glycoproteins encoded by the (multi-drug resistance) mdr genes play a central role in the resistance of tumor cells to a wide range of anti-cancer drugs. Modulation of P-glycoprotein function could therefore provide a means of sensitising tumor cells to chemotherapy. Studies in this context have c