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Multi-Component One-Pot Synthesis of the Tumor-Associated Carbohydrate Antigen Globo-H Based on Preactivation of Thioglycosyl Donors.

โœ Scribed by Zhen Wang; Luyuan Zhou; Kheireddine El-Boubbou; Xin-shan Ye; Xuefei Huang


Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Human milk contains a variety of biologically important oligosaccharides which reflect the lactating mothers Lewis blood group. [1] Antigens N3, known as N3 major and N3 minor, are examples of such milk-derived octasaccharides (Scheme 1). [2] N3 major, difucosyllacto-N-hexose (1), is the major compo