Mucous membrane plasmacytosis of the nose in a patient affected by B-cell chronic lymphocytic leukemia
β Scribed by Massimiliano Garzaro; Giancarlo Pecorari; Matteo Pezzoli; Marisa Arrondini; Domenico Novero; Juri Nadalin; Carlo Giordano
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 312 KB
- Volume
- 266
- Category
- Article
- ISSN
- 0302-9530
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B-cell chronic lymphocytic leukemia (B-CLL) is characterized by the slow and progressive accumulation of monoclonal apparently mature, CD5 Ψ B lymphocytes. The majority of circulating cells appear to be nondividing, and it has been suggested that a prolonged life span is mainly responsible for the a
The karyotypes of 21 patients with chronic B cell leukemia were studied using lymphoblastoid cell lines obtained with the aid of the Epstein-Barr virus. Ten patients had a normal karyotype and eleven patients, an abnormal. There is no single characteristic anomaly, but certain types were more freque
## Background Remarkable advance in the knowledge of the biology and treatment of chronic lymphocytic leukaemia (CLL) has been noted in recent years. CLL resembles several heterogeneous diseases with variable morphological features. New agents with antileukemic activity have been introduced recent