Mucosal IgA defect in primary biliary cirrhosis
โ Scribed by Annarosa Floreani; Anna Baragiotta; Daniela Pizzuti; Diego Martines; Attilio Cecchetto; Silvia Chiarelli
- Book ID
- 119392154
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 33 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0002-9270
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๐ SIMILAR VOLUMES
## Anti -mitochondrial antibodies (AMAs) have long been recognized as a serological hallmark of primary biliary cirrhosis (PBC). Although high titers of immunoglobulin (Ig)A AMAs are found in bile, saliva, and urine of patients, a pathogenic role for this antibody has remained elusive. Functional
Primary biliary cirrhosis is infrequently diagnosed in men, so that the clinical, biochemical and histopathological spectrum of this disease in men has not been evaluated. Therefore, we studied 30 men who had a histological diagnosis of primary biliary cirrhosis and had positive tests for antimitoch