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Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: In vitro release kinetics, syringeability, mechanical and mucoadhesive properties

✍ Scribed by David S Jones; A.David Woolfson; Andrew F Brown; Michael J O'Neill

Book ID
114163300
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
64 KB
Volume
49
Category
Article
ISSN
0168-3659

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Formulations containing poloxamer 407 (P407), carbopol 934P (C934P), and propolis extract (PE) were designed for the treatment of periodontal disease. Gelation temperature, in vitro drug release, rheology, hardness, compressibility, adhesiveness, mucoadhesion, and syringeability of formulations were