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Mucins as key molecules for the classification of intestinal metaplasia of the stomach

✍ Scribed by Elisabete Silva; Ana Teixeira; Leonor David; Fátima Carneiro; Celso A. Reis; Joana Sobrinho-Simões; Jacinta Serpa; Enno Veerman; Jan Bolscher; Manuel Sobrinho-Simões


Publisher
Springer
Year
2001
Tongue
English
Weight
238 KB
Volume
440
Category
Article
ISSN
1432-2307

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In order to ascertain whether genetic alterations occur during the early stages of gastric carcinogenesis. abnormal accumulation of p53 protein and mutation of its gene in stomach tissue showing intestinal metaplasia were investigated using immunohistochemistry and polymerase chain reaction-single s