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Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats

โœ Scribed by Jennifer L. Werkheiser; Scott M. Rawls; Alan Cowan


Book ID
113586347
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
225 KB
Volume
547
Category
Article
ISSN
0014-2999

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The effect of โ„ต-opioid agonist U-50, 488
โœ Masuo Ohno; Tsuneyuki Yamamoto; Hiroaki Araki; Showa Ueki ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› Springer ๐ŸŒ English โš– 483 KB

The effect of a selective kappa-opioid agonist, U-50, 488H, on wet-dog shaking (WDS) induced by hippocampal stimulation was investigated and compared with that produced by morphine. U-50, 488H, as well as morphine, inhibited the appearance of WDS in a dose-dependent manner. U-50, 488H was approximat