𝔖 Bobbio Scriptorium
✦   LIBER   ✦

mTOR links oncogenic signaling to tumor cell metabolism

✍ Scribed by Jessica L. Yecies; Brendan D. Manning

Book ID
105797064
Publisher
Springer
Year
2011
Tongue
English
Weight
217 KB
Volume
89
Category
Article
ISSN
0946-2716

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## Abstract Oleanolic acid (OA), a pentacyclic triterpenoid exhibits potent anti‐tumor activity against many tumor cell lines. But the mechanisms through which OA inhibits osteosarcoma cells are not known. The mammalian target of rapamycin (mTOR) serves as a central regulator of cell growth, prolif