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MtDNA mutation associated with mitochondrial dysfunction in megakaryoblastic leukaemic cells

✍ Scribed by Piccoli, C; Ripoli, M; Scrima, R; Stanziale, P; Di Ianni, M; Moretti, L; Biscottini, B; Carella, M; Boffoli, D; Tabilio, A


Book ID
109886810
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
249 KB
Volume
22
Category
Article
ISSN
0887-6924

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## Paalman Transmitochondrial cybrid cell lines homoplasmic for the A8296G mtDNA transition, a mutation associated with several mitochondrial diseases, have a normal oxidative phosphorylation function, as shown by oxygen consumption, lactate production, respiratory enzyme activities, and growth usi