MS87 AGE-RELATED ELEVATED LEVEL OF C-TERMINAL TRUNCATED APOLIPOPROTEIN A-I IN HIGH-DENSITY LIPOPROTEIN WITH AN INCREASE OF CHOLESTERYL ESTER TRANSFER ACTIVITY

Evaluation of G-to-A substitution in the

Evaluation of G-to-A substitution in the apolipoprotein A-I gene promoter as a determinant of high-density lipoprotein cholesterol level in subjects with and without cholesteryl ester transfer protein deficiency

✍ Harukuni Akita; Hitoshi Chiba; Masahiro Tsuji; Shu-Ping Hui; Yukihiro Takahashi; 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 580 KB

The effect of a polymorphism, guanine (G) to adenine (A) substitution in the promoter of apolipoprotein A-I gene at a position 78 bp upstream of the transcription initiation site, on the serum high-density lipoprotein (HDL)-cholesterol level was studied in 168 Japanese subjects with HDL-cholesterol