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MRP as a new predictive marker of tamoxifen efficiency in treatment of estrogen receptor-positive breast cancer

✍ Scribed by T. A. Bogush; E. A. Dudko; E. A. Bogush; M. V. Tikhomirov; V. Yu. Kirsanov; M. I. Davydov

Book ID: 111470064
Publisher: SP MAIK Nauka/Interperiodica
Year: 2010
Tongue: English
Weight: 187 KB
Volume: 430
Category: Article
ISSN: 1607-6729
DOI: 10.1134/s1607672910010114

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A displacement assay with tamoxifen, based on the relative binding affinity of tamoxifen and estradiol for the estrogen receptor (ER), was proposed in 1990 as prognostic indicator for breast-cancer patients. Validation of its predictive results in relation to the outcome of 73 patients with ER ؉ tum