mRNA Transcription linked to the Morphological and Plasma Membrane Changes induced by Cyclic AMP in Tumour Cells

Biochemical and morphological changes in

Biochemical and morphological changes induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat liver cell plasma membrane

✍ John B. Greig; Glenys Osborne 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 598 KB

## Abstract The administration of single oral doses of 200 μg kg^−1^ of 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin to females of the outbred, Lac: P strain of rat results in the formation of hepatic multinucleate cells by cell fusion. Liver cell plasma membranes isolated 6 or 11 days after dosing show