FAS mRNA editing in human systemic lupus
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Jianming Wu; Fenglong Xie; Kun Qian; Andrew W. Gibson; Jeffrey C. Edberg; Robert
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Article
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2011
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John Wiley and Sons
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English
β 476 KB
FAS/FASL system plays a central role in maintaining peripheral immune tolerance. Human Systematic Lupus Erythematosus (SLE) is a prototypic systemic autoimmune disease characterized by expansion of autoreactive lymphocytes. It remains unclear whether a defective FAS/FASL system is involved in the pa