## Abstract ## BACKGROUND The objective of this study was to determine whether HERβ2 overexpression is associated with improved response to neoadjuvant chemotherapy with 5βfluorouracil, doxorubicin, cyclophosphamide (FAC) in patients with breast carcinoma. ## METHODS Ninetyβseven patients with S
MRI Phenotype Is Associated With Response to Doxorubicin and Cyclophosphamide Neoadjuvant Chemotherapy in Stage III Breast Cancer
β Scribed by Laura Esserman; Elizabeth Kaplan; Savanah Partridge; Debasish Tripathy; Hope Rugo; John Park; Shelley Hwang; Henry Kuerer; Dan Sudilovsky; Ying Lu; Nola Hylton
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 882 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1068-9265
No coin nor oath required. For personal study only.
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## Abstract ## BACKGROUND Clinical investigations have shown that in patients with breast carcinoma, tumors that overexpress the __erb__βB2 gene are less responsive to certain chemotherapy regimens compared with tumors that express low levels of __ErbB2__, suggesting that ErbB2 overexpression may