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MRI of “diffusion” in the human brain: New results using a modified CE-FAST sequence

✍ Scribed by Klaus-Dietmar Merboldt; Harald Bruhn; Jens Frahm; Michael L. Gyngell; Wolfgang Hänicke; Michael Deimling


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
495 KB
Volume
9
Category
Article
ISSN
0740-3194

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✦ Synopsis


Diffusion-weighted' MRI in the normal human brain and in a patient with a cerebral metastasis is demonstrated. The method employed was a modified CE-FAST sequence with imaging times of only 6-10 s using a conventional 1 S-T whole-body MRI system (Siemens Magnetom). As with previous phantom and animal studies, the use of strong gradients together with macroscopic motions in vivo causes unavoidable artifacts in diffusion-weighted images of the human brain. While these artifacts are shown to be considerably reduced by averaging of 8-16 images, the resulting diffusion contrast is compromised by unknown signal losses due to motion.