MRI in ocular drug delivery
β Scribed by S. Kevin Li; Martin J. Lizak; Eun-Kee Jeong
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 325 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1230
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The main goal of local drug delivery is to increase the concentration of a specific therapeutic agent in a target tissue with minimal nontarget distribution. Compared to systemic therapy, local drug delivery provides a high level of therapeutic efficacy with minimal systemic effects. Th
## Abstract This study sought to develop an injectable formulation for longβterm ocular delivery of fluocinolone acetonide (FA) by dissolving the antiβinflammatory drug and the biodegradable polymer poly(propylene fumarate) (PPF) in the biocompatible, waterβmiscible, organic solvent __N__βmethylβ2β
The objective of this study was to examine the ocular absorption behavior of an amphiphilic prodrug after instillation onto the cornea of rabbits. A micellar solution of O-palmitoyl tilisolol (PalTL), an amphiphilic prodrug, was prepared. After instillation of tilisolol (TL) and PalTL, the drug conc
Poly(D,L-lactide-co-glycolide) nanospheres incorporating flurbiprofen were prepared by the solvent displacement technique for purposes of assessing (i) drugpolymer physicochemical interactions, (ii) flurbiprofen release from the polymer matrix and (iii) eye permeation of the drug formulated in the c