MRI and Diffusion MRI in nonparaneoplastic limbic encephalitis

✍ Scribed by R.N. Sener

• Publisher: Elsevier Science
• Year: 2002
• Tongue: English
• Weight: 306 KB
• Volume: 26
• Category: Article
• ISSN: 0895-6111
• DOI: 10.1016/s0895-6111(02)00022-8

✦ Synopsis

This paper reports an 65-year-old woman with nonparaneoplastic limbic encephalitis. On MRI and diffusion MRI, diffuse and symmetrical, bilateral high-signal lesions were evident in the medial temporal lobes. The affected areas were hyperintense on b= 1000 s/mm(2) (heavily diffusion-weighted or true diffusion) images, a pattern similar to cytotoxic edema. However, apparent diffusion coefficient (ADC) values read directly from corresponding ADC maps at each temporal lobe were within normal limits: 0.96 and 0.97 x 10 x (-3) mm(2)/s, respectively, excluding cytotoxic edema. The changes were shown to be resolved on a 9-month follow-up MRI.