## Abstract Hippel‐Lindau disease is an autosomal dominant disorder characterized by tumors of the central nervous system and abdominal viscera. Frequent multisystem radiologic evaluation of persons at risk is desirable. Twenty‐seven patients with Hippel‐Lindau disease or a family history of the di
MR imaging of soft-tissue masses: Role of gadopentetate dimeglumine
✍ Scribed by Richard A. Benedikt; James S. Jelinek; Mark J. Kransdorf; Richard P. Moser; B. Hudson Berrey
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 776 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
To assess the effectiveness of gadopentetate dimeglumine in the magnetic resonance (MR) imaging evaluation of soft‐tissue masses without osseous involvement, 30 patients underwent MR imaging before and after administration of contrast material (0.1 mmol/ kg) of the 30 lesions, 22 were benign and eight were malignant; histologic confirmation was available in all lesions except one benign lesion. Overall, enhancement was detected in 26 (87%) of 30 lesions: 18 (82%) of the 22 benign lesions and eight (100%) of eight malignant lesions. Enhancement was characterized as homogeneous (two [11%] benign lesions, two [25%] malignant lesions), inhomogeneous (11 [61%] benign lesions, six [75%] malignant lesions), or peripheral (five [28%] benign lesions, no malignant lesions) of the 19 lesions assessed for a change in enhancement over time, seven (37%) showed an increase and two (11%) showed a decrease in signal intensity. The authors conclude that benign and malignant soft‐tissue lesions could not be differentiated solely on the basis of enhancement (pattern, degree, or time course).
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