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MR imaging of ovarian tumors using folate-receptor-targeted contrast agents

โœ Scribed by Zhen J. Wang; Sophie Boddington; Michael Wendland; Reinhard Meier; Claire Corot; Heike Daldrup-Link


Book ID
105940924
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
408 KB
Volume
38
Category
Article
ISSN
0301-0449

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The need to develop target-specific MRI contrast agents to aid in disease characterization remains highly essential. In this study, we present a generation four polyamidoamine (PAMAM) folate-dendrimer that specifically targets the high affinity folate receptor (hFR) overexpressed on more than 80% of