## Abstract M2R melanoma tumors in male C57 black mice were used to correlate magnetic resonance (MR) images with the corresponding histologic slices and to determine if analysis of the achievable correlation can provide a basis for predicting gross histologic features with MR imaging alone. The MR
MR imaging of Ho:YAG laser diskectomy with histologic correlation
✍ Scribed by Jeffrey J. Phillips; George E. Kopchok; Shi-Kaung Peng; Mark P. Mueller; Rodney A. White
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 620 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Twelve cadaveric vertebral specimens were imaged after holmium yttrium aluminum garnet (Ho:YAG) laser diskectomy to determine the usefulness of magnetic resonance (MR) imaging in evaluating treatment outcome. The Ho:YAG laser was operated at 1.0‐2.0 J per pulse, 5 Hz, and 250‐usec pulse width. The total energy varied between 600 and 2,700 J. Two distinct patterns emerged on MR images. Tissue ablation at higher power (1.5 and 2.0 J per pulse) produced discrete signal voids that correlated with areas of laser‐induced ablation identified at gross inspection. More subtle changes, characterized by a high‐signal‐intensity ring, were seen in the specimens lased at 1.0 J per pulse. The latter appearance corresponded to incomplete vaporization of diskal tissue, a broader zone of minimal thermal injury, and sparing of adjacent vertebral endplates. Total mass loss did not appear to be affected by the choice of power setting (1.0 vs 1.5 J per pulse), with total laser energy held constant.
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