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MR imaging and proton spectroscopy of the brain in posttraumatic cortical blindness

✍ Scribed by Stephan R. Felber; Armin R. Ettl; Günther G. Birbamer; Gaby Luz; Franz T. Aichner

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
363 KB
Volume
3
Category
Article
ISSN
1053-1807

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Magnetic resonance (MR) imaging and localized proton MR spectroscopy of the occipital lobes were performed in a patient with cortical blindness following brain trauma. Computed tomography (CT) scans and MR images of the visual cortex were normal in the acute stage. Six weeks after the trauma, MR images showed cortical lesions in both occipital lobes, while the spectra showed elevated lactate and decreased N‐acetyl aspartate levels relative to those of healthy volunteers. One year later, visual acuity had improved and follow‐up studies revealed an increase in the ratios of N‐acetyl aspartate to choline and creatine. These results demonstrate that parenchymal lesions may develop in brain regions that appear normal at CT and MR imaging during the acute stage after trauma. Metabolic changes can be observed in these areas by means of localized proton MR spectroscopy.

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