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MR gradient echo imaging of intravascular blood oxygenation: T2* determination in the presence of flow

✍ Scribed by Dr. Daisy Chien; David L. Levin; Charles M. Anderson

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
589 KB
Volume
32
Category
Article
ISSN
0740-3194

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✦ Synopsis

Abstract

The T~2~* relaxation time of blood varies with its oxygen saturation. To evaluate the feasibility of imaging intravascular blood oxygenation in humans using a conventional 1.5T MR system, we have implemented a method to measure T~2~* of blood despite the presence of pulsatile flow. The method was tested in a) stationary and flow phantoms, b) blood samples at different levels of oxygen saturation, and c) a human hypoxia model. Our results demonstrate the ability of cardiac‐triggered, flow compensated gradient echo imaging to obtain reproducible T~2~* measurements of flowing blood in vivo.

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