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MR Breast screening in patients with genetic mutation

✍ Scribed by E. Daguet; C. Malhaire; C. Hardit; A. Athanasiou; C. El Khoury; F. Thibault; L. Ollivier; A. Tardivon


Book ID
113542997
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
47 KB
Volume
33
Category
Article
ISSN
0899-7071

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In the present study, leukocyte DNA from 143 patients with familial clustering of breast and/or ovarian cancer and tumour DNA from 96 breast carcinomas were screened for base mutations in the estrogen receptor gene (ESR). Three patients with a family history of cancer were carrying a Gly160Cys germl