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MPO and SOD2 polymorphisms, gender, and the risk of non-small cell lung carcinoma

✍ Scribed by Geoffrey Liu; Wei Zhou; Lisa I. Wang; Sohee Park; David P. Miller; Li Lian Xu; John C. Wain; Thomas J. Lynch; Li Su; David C. Christiani

Book ID
116333228
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
137 KB
Volume
214
Category
Article
ISSN
0304-3835

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## Abstract ## BACKGROUND Exogenous reactive oxygen species (ROS) induces DNA damage. Manganese superoxide dismutase (SOD2) catalyzes the dismutation of superoxide radicals, a major type of ROS, into hydrogen peroxide. __p53__ is a tumor suppressor gene, and X‐ray cross‐complementing group 1 (XRCC