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MP41-15 EVALUATION OF ANDROGEN RECEPTOR FUNCTION IN PROSTATE CANCER

✍ Scribed by Dobi, Albert; Young, Denise; Ravindranth, Lakshmi; Huang, Wei; Brothers, Aaron; Sharad, Shashwat; Li, Hua; Petrovics, Gyorgy; McLeod, David G.; Sesterhenn, Isabell A.; Srivastava, Shiv

Book ID
122310025
Publisher
Lippincott Williams and Wilkins
Year
2014
Tongue
English
Weight
257 KB
Volume
191
Category
Article
ISSN
0022-5347

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The androgen receptor (AR) signaling pathway plays an important role during the development of the normal prostate gland, but also during the progression of prostate cancer on androgen ablation therapy. Mutations in the AR gene emerge to keep active the AR signaling pathway and to support prostate c