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MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2

✍ Scribed by Pelletier, Nadine; Champagne, Nathalie; Stifani, Stefano; Yang, Xiang-Jiao


Book ID
110066563
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
383 KB
Volume
21
Category
Article
ISSN
0950-9232

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## Abstract The Runx2 transcription factor is a key regulator of osteoblast differentiation. In response to 1Ξ±,25 dihydroxy vitamin D3, Runx2 may interact with the 1Ξ±,25 dihydroxy vitamin D3 receptor (VDR) in the promoter of target genes, producing a synergic activation of their transcription. Prev