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Movement of the S4-S5 Linker of KvAP during Gating

✍ Scribed by Faure, Elise; McGuire, Hugo; Marsolais, Mireille; Blunck, Rikard

Book ID
119209297
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
39 KB
Volume
102
Category
Article
ISSN
0006-3495

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The human ether‐à‐go‐go related gene (hERG) encodes a protein that forms a voltage‐gated potassium channel and plays an important role in the heart by controlling the rapid delayed rectifier K^+^ current (__I__~Kr~). The S4–S5 linker was shown to be important for the gating of the hERG channel. Nucl