MOVEMENT DISORDERS 4

✍ Scribed by Anthony H.V. Schapira, Anthony E.T. Lang and Stanley Fahn (Eds.)

• Publisher: Saunders
• Year: 2010
• Tongue: English
• Leaves: 476
• Series: Blue Books of Neurology 34
• Edition: 1
• Category: Library

✦ Synopsis

Multiple Sclerosis 3 emphasizes the latest in the pharmacologic treatment of this incurable inflammatory demyelinating disorder. Primary editors Claudia Lucchinetti, MD, and Reinhard Hohlfeld, MD, with the aid of all new contributors, present a complete and current reference on multiple sclerosis that includes discussions of such hot topics as Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair. Distinguish between MS and other similar demyelinating disorders and know the best and most aggressive methods of treatment. This title in the Blue Books of Neurology series is exactly what you need to treat the disease and its relapses.Covers the latest clinical advances and relevant discussions-Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair-to bring you up to date and keep your practice state-of-the-art.Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy.Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment.Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders.Presents expert new editors and experienced contributing authors for the most current and relevant practice information.Emphasizes the pharmacologic management of patients with multiple sclerosis to address treating the actual disease and its relapses as well as treating the symptoms.

✦ Table of Contents

Content:
Copyright
Page iv

BLUE BOOKS OF NEUROLOGY
Pages v-vii

CONTRIBUTING AUTHORS
Pages xiii-xxii
Kailash Bhatia, Vincenzo Bonifati, David James Brooks, Jonathan M. Brotchie, David John Burn, Yaroslau Compta, Ted M. Dawson, Gunther Deuschl, Dennis W. Dickson, Stanley Fahn, Matthew James Farrer, Alfonso Fasano, Alessandro Ferraris, Susan Fox, Carles Gaig, Thomas Gasser, Felix Geser, Amitabh Gupta, Glenda Halliday, Clement Hamani, et al.

SERIES PREFACE
Page xxiii
Anthony H.V. Schapira, Martin A. Samuels

PREFACE
Page xxv
Anthony schapira, Anthony Lang, Stanley Fahn

Chapter 1 - Functional Anatomy and Pathophysiology of the Basal Ganglia
Pages 1-13
Jonathan M. Brotchie, José A. Obeso

Chapter 2 - Genetics of Parkinson's Disease—An Overview
Pages 15-39
Christine Klein

Chapter 3 - α-Synuclein and Parkinson's Disease
Pages 40-53
Thomas Gasser

Chapter 4 - PARK2: Parkin Mutations Responsible for Familial Parkinson's Disease
Pages 54-65
Nobutaka Hattori, taku Hatano, Yutaka Machida, Shigeto Sato, Shin-Ichiro Kubo

Chapter 5 - PINK1 (PARK6) and Parkinson's Disease
Pages 66-82
Enza Maria valente, Alessandro Ferraris

Chapter 6 - DJ-1 (PARK7) and Parkinson's Disease
Pages 83-101
Vincenzo Bonifati

Chapter 7 - LRRK2 and Parkinson's Disease
Pages 102-112
Matthew James Farrer

Chapter 8 - Environmental Factors and Parkinson's Disease
Pages 113-131
Caroline M. Tanner

Chapter 9 - Pathology of Parkinson's Disease
Pages 132-154
Glenda Halliday, Karen Murphy

Chapter 10 - Pathogenesis of Parkinson's Disease
Pages 155-169
Amitabh Gupta, Ted M. Dawson

Chapter 11 - Imaging in Parkinson's Disease
Pages 170-187
David James Brooks

Chapter 12 - Dementia in Parkinson's Disease
Pages 188-212
David John Burn

Chapter 13 - Psychiatric Issues in Parkinson's Disease
Pages 213-228
Daniel Weintraub

Chapter 14 - Nonmotor Aspects of Parkinson's Disease
Pages 229-251
Eduardo Tolosa, Joan Santamaria, Carles Gaig, Yaroslau Compta

Chapter 15 - Therapy of the Motor Features of Parkinson's Disease
Pages 252-272
Susan Fox, Anthony E. Lang

Chapter 16 - Surgical Therapy for Parkinson's Disease
Pages 273-286
Adrian W. Laxton, Clement Hamani, Andres M. Lozano

Chapter 17 - Cell-Based and Gene-Based Therapy for Parkinson's Disease
Pages 287-300
C. Warren Olanow

Chapter 18 - Neuroprotection in Parkinson's Disease
Pages 301-320
Anthony H.V. Schapira

Chapter 19 - Etiology, Pathology, and Pathogenesis
Pages 321-339
Felix Geser, Kurt Jellinger, Martin Köllensperger, Nadia Stefanova, Gregor K. Wenning

Chapter 20 - Multiple System Atrophy: Clinical Features and Management
Pages 340-359
Werner Poewe, Klaus Seppi

Chapter 21 - Progressive Supranuclear Palsy
Pages 361-374
Huw R. Morris

Chapter 22 - Corticobasal Ganglionic Degeneration
Pages 375-396
Keith A. Josephs

Chapter 23 - Frontotemporal Dementia
Pages 397-416
Christian W. Wider, Dennis W. Dickson, Rosa Rademakers, Zbigniew K. Wszolek

Chapter 24 - Etiology, Pathology, and Pathogenesis
Pages 417-431
Patrick Weydt, G. Bernhard Landwehrmeyer, Albert C. Ludolph

Chapter 25 - Clinical Features and Care
Pages 432-456
Ira Shoulson

Chapter 26 - The Genetics and Pathogenesis of Dystonia
Pages 457-473
Thomas T. Warner

Chapter 27 - Management
Pages 474-488
Elena Moro, Marie Vidailhet

Chapter 28 - Paroxysmal Dyskinesias
Pages 489-505
Kailash P. Bhatia, Susanne A. Schneider

Chapter 29 - Essential Tremor and Other Tremors
Pages 506-557
Günther Deuschl, Alfonso Fasano

Chapter 30 - Other Choreas
Pages 558-586
Ruth H. Walker

Chapter 31 - Restless Legs Syndrome
Pages 587-621
Wayne Hening, Claudia Trenkwalder

Chapter 32 - Startled People
Pages 622-629
Philip Thompson

Chapter 33 - Psychogenic Movement Disorders
Pages 630-650
Madhavi Thomas, Joseph Jankovic

Chapter 34 - Tics and Gilles de la Tourette Syndrome
Pages 651-663
Harvey S. Singer

Index
Pages 665-684