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Mouse Strain Differences in Susceptibility to Cerebral Ischemia Are Related to Cerebral Vascular Anatomy

✍ Scribed by Barone, F. C.; Knudsen, D. J.; Nelson, A. H.; Feuerstein, G. Z.; Willette, R. N.

Book ID
109870699
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
853 KB
Volume
13
Category
Article
ISSN
0271-678X

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## Abstract We have demonstrated previously that the protein tyrosine phosphatase SHP‐1 seems to play a role in glial development and is upregulated in non‐dividing astrocytes after injury. The present study examines the effect of loss of SHP‐1 on the CNS response to permanent focal ischemia. SHP‐1