## Abstract Interferon‐β (IFN‐β) has been used as an antitumor drug against human glioma, melanoma and medulloblastoma since the 1980s. Recently, we developed a new gene therapy using the __IFN__‐β gene against malignant gliomas and then began clinical trials in 2000. Since stimulation of immune sy
Mouse ovarian tumor cells: An experimental model for progestin-mediated radiotherapy
✍ Scribed by Rosalyn D. Blumenthal; William H. McLaughlin; Jerold J. Jordan; Ellen V. Cryan; William D. Bloomer
- Book ID
- 102439625
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 489 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
✦ Synopsis
Mouse ovarian tumor (MOT) cells have been grown in C3HeB/FeJ mice as an ascites and as a subcutaneous tumor and in cell culture as a suspension. These cells contain saturable, high-affinity, specific progesterone receptors. Estrogen receptors were not detectable in these cells. MOT cells can be used as both an in vivo and an in vitro model for progestinmediated radiotherapy.
📜 SIMILAR VOLUMES
## Abstract We have developed a murine mammary tumor cell line, MC4‐L4, and after 15 passages, a spindle‐shaped population became evident. The cuboidal cells, MC4‐L4E, cloned by limit dilution, proved to be epithelial tumor cells. When inoculated in syngeneic mice, they gave rise to invasive metast