Ξ±-Synuclein abnormalities in mouse model
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Eugenia Yakunin; Ann Moser; Virginie Loeb; Ann Saada; Phyllis Faust; Denis I. Cr
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Article
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2009
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John Wiley and Sons
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English
β 330 KB
## Abstract Ξ±βSynuclein (Ξ±S) is a presynaptic protein implicated in Parkinson's disease (PD). Growing evidence implicates mitochondrial dysfunction, oxidative stress, and Ξ±Sβlipid interactions in the gradual accumulation of Ξ±S in pathogenic forms and its deposition in Lewy bodies, the pathological