The GRACILE mutation introduced into Bcs
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Per Levéen; Heike Kotarsky; Matthias Mörgelin; Riitta Karikoski; Eskil Elmér; Vi
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Article
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2010
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John Wiley and Sons
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English
⚖ 754 KB
Mitochondrial dysfunction is an important cause for neonatal liver disease. Disruption of genes encoding oxidative phosphorylation (OXPHOS) components usually causes embryonic lethality, and thus few disease models are available. We developed a mouse model for GRACILE syndrome, a neonatal mitochondr