✦ LIBER ✦

Mouse mammary-tumor virus: The basics of an oncogenic retrovirus. Steiner Young Investigator Award lecture 1995

✍ Scribed by Hans Acha-Orbea

Publisher: John Wiley and Sons
Year: 1996
Tongue: French
Weight: 221 KB
Volume: 66
Category: Article
ISSN: 0020-7136
DOI: 10.1002/(sici)1097-0215(19960503)66:3<285::aid-ijc1>3.0.co;2-v

No coin nor oath required. For personal study only.

✦ Synopsis

It was a coincidence that we became interested in research on oncogenic retroviruses. We were following a surprising immunological observation made over 20 years ago by Festenstein (1973, review). At that time, it was known that mixed lymphocyte cultures between cells expressing different major-histocompatibility-complex(MHC) molecules stimulated a very strong reaction activating 1 to 5% of peri heral T lymphocytes. The frequency of reactive T cells was 103 to lo4 times