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Mouse LGI3 gene: Expression in brain and promoter analysis

✍ Scribed by Sang Eun Lee; A-Young Lee; Woo-Jae Park; Dong Ha Jun; Nyoun Soo Kwon; Kwang Jin Baek; Yang-Gyun Kim; Hye-Young Yun

Book ID
116507319
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
994 KB
Volume
372
Category
Article
ISSN
0378-1119

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## Abstract D‐3‐Phosphoglycerate dehydrogenase (Phgdh; EC 1.1.1.95) is a necessary enzyme for de novo L‐serine biosynthesis via the phosphorylated pathway. Targeted disruption of the mouse __Phgdh__ gene has been shown to result in embryonic lethality, accompanied by severe abnormalities in brain d