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Mouse and guinea pig models for testing new tuberculosis vaccines

✍ Scribed by Ian M. Orme


Book ID
113937809
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
160 KB
Volume
85
Category
Article
ISSN
1472-9792

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A derivation, more rigorous than hitherto, of the Relative Alkylation Index (RAI) as a quantifier of carrier protein haptenation in skin sensitization tests is presented. It is shown that the RAI, which is a composite parameter made up of dose, reactivity and lipophilicity terms, is likely to requir