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Mouse allergen-specific immunoglobulin G4 and risk of mouse skin test sensitivity

โœ Scribed by E. C. Matsui; G. B. Diette; E. J. M. Krop; R. C. Aalberse; A. L. Smith; P. A. Eggleston


Book ID
108687791
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
119 KB
Volume
36
Category
Article
ISSN
0954-7894

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A derivation, more rigorous than hitherto, of the Relative Alkylation Index (RAI) as a quantifier of carrier protein haptenation in skin sensitization tests is presented. It is shown that the RAI, which is a composite parameter made up of dose, reactivity and lipophilicity terms, is likely to requir