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Mouse A6–positive hepatic oval cells also express several hematopoietic stem cell markers

✍ Scribed by Bryon E. Petersen; Brian Grossbard; Heather Hatch; Liya Pi; Jie Deng; Edward W. Scott

Book ID
111722157
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
612 KB
Volume
37
Category
Article
ISSN
0270-9139

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Hepatic oval cells (HOC) are a small subpopulation of cells found in the liver when hepatocyte proliferation is inhibited and followed by some type of hepatic injury. HOC can be induced to proliferate using a 2-acetylaminofluorene (2-AAF)/hepatic injury (i.e., CCl 4 , partial hepatectomy [PHx]) prot