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Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury

โœ Scribed by Y Chen; L Lomnitski; D.M Michaelson; E Shohami


Book ID
117491786
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
196 KB
Volume
80
Category
Article
ISSN
0306-4522

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Apolipoprotein E (apoE)-deficient mice have learning and memory impairments that are associated with specific neurochemical changes and hyperphosphorylation of distinct epitopes of the cytoskeletal protein tau. Furthermore, such mice are highly susceptible to the sequelae of brain trauma and their a