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Most effective stimulation site in subthalamic deep brain stimulation for Parkinson's disease

✍ Scribed by Jan Herzog; Urban Fietzek; Wolfgang Hamel; Andre Morsnowski; Frank Steigerwald; Bettina Schrader; Dieter Weinert; Gerd Pfister; Dieter Müller; Hubertus M. Mehdorn; Günther Deuschl; Jens Volkmann

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
303 KB
Volume
19
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

The optimal stimulation site in subthalamic deep brain stimulation (STN‐DBS) was evaluated by correlation of the stereotactic position of the stimulation electrode with the electrophysiologically specified dorsal STN border. In a series of 25 electrodes, best clinical results with least energy consumption were found in contacts located in the dorsolateral border zone, whereas contacts within the subthalamic white matter, e.g., zona incerta, were significantly less effective. We suggest that the dorsolateral STN border should be covered by STN‐DBS. © 2004 Movement Disorder Society

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