‘Most bothersome symptom’ is not independently associated to response to PPI treatment in patients from general practice

Rapid response to paroxetine is associat

Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients

✍ Reiji Yoshimura; Wakako Umene-Nakano; Akihito Suzuki; Nobuhisa Ueda; Kyoko Miyam 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 115 KB 👁 1 views

## Abstract In the present study, we investigated the relationship between the serotonin transporter gene linked polymorphic regions (5‐HTTLPR) or plasma paroxetine levels and clinical response to paroxetine in depressed patients. Sixty patients who met the DSM‐IV criteria for major depressive diso