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Mosaic X chromosome aneuploidy can help to explain the male-to-female ratio in autism

✍ Scribed by Ivan Y. Iourov; Yuri B. Yurov; Svetlana G. Vorsanova


Book ID
116744131
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
33 KB
Volume
70
Category
Article
ISSN
0306-9877

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## Abstract In this paper, we hypothesize that X chromosome‐associated mechanisms, which affect X‐linked genes and are behind the immunological advantage of females, may also affect X‐linked microRNAs. The human X chromosome contains 10% of all microRNAs detected so far in the human genome. Althoug