Morquio disease, type B: Activation of GM1-β-galactosidase by GM1-activator protein
✍ Scribed by E. Paschke; H. Kresse
- Book ID
- 115756027
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 793 KB
- Volume
- 109
- Category
- Article
- ISSN
- 0006-291X
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Alterations in GLB1, the gene coding for acid b-D-galactosidase (b-Gal), can result in GM1 gangliosidosis (GM1), a neurodegenerative disorder, or in Morquio B disease (MBD), a phenotype with dysostosis multiplex and normal central nervous system (CNS) function. While most MBD patients carry a common
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