The purpose of this study was to determine the degree of bilateral variability in cross-sectional geometric properties of the adult canine proximal femur and to use these data to determine minimum detectable treatment effects in paired and independent experimental designs. Thirteen pairs of canine f
Morphometric and anisotropic symmetries of the canine distal femur
β Scribed by Dr. J. L. Kuhn; R. W. Goulet; M. Pappas; S. A. Goldstein
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 414 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0736-0266
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β¦ Synopsis
Abstract
The purpose of this study was to investigate the homotypical variation in morphologic and anisotropic properties of trabecular bone from paired canine distal femurs. A microcomputed tomography system was used to produce threeβdimensional digital reconstructions of the trabecular bone structures. The results showed that the mean bilateral differences in all bone morphology variables were < 5%. Differences in measures of degree of anisotropy were also < 5% between matched sites from left and right sides. In general, the bilateral difference in angle of orientation was < 15%. These data are valuable for calculating the appropriate sample size to use in experiments using the contralateral canine femur as a control. The results and general approach of the study may have significance for the future use of other contralateral trabecular bone sites as controls.
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## Abstract Fluorochrome labeling and microcomputed tomography were used to completely characterize the regional and ageβrelated variations in bone growth in the distal femur of the very young rabbit. Use of the microcomputed tomography system, in conjunction with the more routine fluorochrome labe