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Morphology, mineral initiation and gene expression of human primary osteoblasts cultured on dense fibrillar collagen matrices

✍ Scribed by J. Silvent; N. Nassif; M.-M. Giraud-Guille; J.-Y. Sire


Book ID
116324326
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
57 KB
Volume
48
Category
Article
ISSN
8756-3282

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Simvastatin and atorvastatin enhance gen
✍ Silvia Ruiz-Gaspa; Xavier Nogues; Anna Enjuanes; Joan C. Monllau; Josep Blanch; πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 139 KB

## Abstract To clarify the mechanism of the stimulatory effect of statins on bone formation, we have assessed the effect of simvastatin and atorvastatin on osteoblast activity by analysing cell proliferation, as well as collagen, osteocalcin, and bone morphogenetic protein‐2 (__BMP2__) gene express