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Morphological and functional effects of PACAP in 6-hydroxydopamine-induced lesion of the substantia nigra in rats

✍ Scribed by Dóra Reglődi; Andrea Tamás; Andrea Lubics; Luca Szalontay; István Lengvári


Book ID
116857514
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
622 KB
Volume
123
Category
Article
ISSN
0167-0115

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✍ A. J. Stoessl; C. T. Dourish; S. D. Iversen 📂 Article 📅 1987 🏛 Springer 🌐 English ⚖ 669 KB

Apomorphine-induced yawning was studied in male rats with bilateral 6-hydroxydopamine lesions of the substantia nigra. Apomorphine 10, 20 and 50 lag/kg SC induced dose-dependent yawning in unoperated controls and animals with sham lesions. In the lesioned animals (in which the mean striatal dopamine