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Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL

✍ Scribed by Aileen J Anderson; Sarah Stoltzner; Florence Lai; Joseph Su; Ralph A Nixon

Book ID
117411059
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
633 KB
Volume
21
Category
Article
ISSN
0197-4580

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## Abstract ## Objective Virtually all adults with Down syndrome (DS) have neuropathological manifestations of Dementia in Alzheimer's disease (DAD) but not all develop clinical psychopathology. The effect of allelic variants of Apolipoprotein (APOE) gene in development and progression of DAD and