## BACKGROUND. When a change of opioid is considered, equianalgesic dose tables are used. These tables generally propose a dose ratio of 5:l between morphine and hydromorphone. In the case of a change from subcutaneous hydromorphone to methadone, dose ratios ranging from 1:6 to 1:10 are proposed.
✦ LIBER ✦
Morphine-Methadone Opioid Rotation in Cancer Patients: Analysis of Dose Ratio Predicting Factors
✍ Scribed by Miguel Angel Benítez-Rosario; Antonio Salinas-Martín; Armando Aguirre-Jaime; Lina Pérez-Méndez; Manuel Feria
- Book ID
- 113741356
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 107 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0885-3924
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## Background: Current equianalgesic reference tables, based largely on single dose studies, give dose ratios of 1:1 to 4:1 for oral morphine to oral methadone, which possibly are inaccurate in patients with cancer pain who are exposed to multiple doses of these opioids. the purpose of this study w
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