Galectin-3 is a -galactoside-binding protein synthesized by macrophages and other inflammatory cells and expressed in various branching epithelia, including the developing kidney. The expression of galectin-3 has been studied in a rat model of acute mesangial proliferative glomerulonephritis in whic
โฆ LIBER โฆ
Morphine-induced macrophage activity modulates mesangial cell proliferation and matrix synthesis
โ Scribed by Singhal, Pravin C; Mattana, Joseph; Garg, Puneet; Arya, Mukul; Shan, Zihe; Gibbons, Nora; Franki, Nicholas
- Book ID
- 109884347
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 885 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0085-2538
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## Abstract Transcription factor Spโ1 is an important fibrogenic factor that is involved in the pathogenesis of diabetic nephropathy. In this study, we examined the effect of Sp1 decoy oligodeoxynucleotides (ODNs) on the extracellular matrix (ECM) gene expression in cultured rat mesangial cells (RM