Comparison of tolerance development and
✍
Erzsébet Miglécz; J. I. Székely; Zsuzsa Dunai-Kovács
📂
Article
📅
1979
🏛
Springer
🌐
English
⚖ 532 KB
The tolerance-development capacities of beta-endorphin, [D-Met2, Pro5]-enkephalinamide, and morphine were compared in rats, and the dependence capacity of morphine was compared with that of the enkephalin analogue in mice. Tolerance to the analgesic effect, as measured by the tail-flick test, develo