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Morphine and [D-Met2,Pro5]enkephalinamide do not show specific neuroleptic activity

✍ Scribed by Eleonóra Sineger; Katalin Horváth; Erzsébet Miglécz; István Tarnawa; Ferenc Andrási; József I. Székely


Book ID
115877017
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
749 KB
Volume
80
Category
Article
ISSN
0014-2999

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✍ Erzsébet Miglécz; J. I. Székely; Zsuzsa Dunai-Kovács 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 532 KB

The tolerance-development capacities of beta-endorphin, [D-Met2, Pro5]-enkephalinamide, and morphine were compared in rats, and the dependence capacity of morphine was compared with that of the enkephalin analogue in mice. Tolerance to the analgesic effect, as measured by the tail-flick test, develo